HAWKSWORTH, GABRIELLE, M.: search on Z-Library

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1

Metabolism of cisplatin to a Nephrotoxin [Toxicology, 257(3), 174–175, doi 10.1016/j.tox.2008.12.014]

Richard D. Wainford, Richard J. Weaver, Keith N. Stewart, Paul Brown, Gabrielle M. Hawksworth

Journal:

Year:

2009

Language:

english

File:

PDF, 94 KB

english, 2009

2

Role of metabolites in MDMA (ecstasy)-induced nephrotoxicity: an in vitro study using rat and human renal proximal tubular cells

Márcia Carvalho, Gabrielle Hawksworth, Nuno Milhazes, Fernanda Borges, Terrence J. Monks, Eduarda Fernandes, Félix Carvalho, Maria Bastos

Journal:

Archives of Toxicology

Year:

2002

Language:

english

File:

PDF, 369 KB

english, 2002

3

Metabolism in the Rat of Some Pyrazine Derivatives having Flavour Importance in Foods

Hawksworth, Gabrielle, Scheline, Ronald R.

Journal:

Year:

1975

Language:

english

File:

PDF, 707 KB

english, 1975

4

Halothane uptake and nitrous oxide concentration : Arterial halothane levels during Caesarean section

M.E. Tunstall, GABRIELLE M. HAWKSWORTH

Journal:

Year:

1981

Language:

english

File:

PDF, 416 KB

english, 1981

5

Inhibition of antipyrine metabolite formation by ketoconazole in rat and human hepatic microsomes

HAWKSWORTH, GABRIELLE M., BROWN, JUDITH E., BURKE, M. DANNY, TAN, KEITH K. C.

Journal:

Biochemical Society Transactions

Year:

1986

Language:

english

File:

PDF, 225 KB

english, 1986

6

Inside-out vesicles expressing multi-drug resistance protein (MRP) 2 and MRP4: Evaluation using fluorescent and radiolabelled substrates

Zoe Riches, Helen Pearce, Gabrielle M. Hawksworth

Journal:

Year:

2010

Language:

english

File:

PDF, 63 KB

english, 2010

7

Can finger-prick sampling replace venous sampling to determine the pharmacokinetic profile of oral paracetamol?

Baba S. Mohammed, Garry A. Cameron, Lindsay Cameron, Gabrielle H. Hawksworth, Peter J. Helms, James S. McLay

Journal:

British Journal of Clinical Pharmacology

Year:

2010

Language:

english

File:

PDF, 580 KB

english, 2010

8

The relation between diet and the gut microflora in man

Drasar, B. S., Crowther, J. S., Goddard, P., Hawksworth, Gabrielle, Hill, M. J., Peach, Susan, Williams, R. E. O., Renwich, A.

Journal:

Proceedings of The Nutrition Society

Year:

1973

Language:

english

File:

PDF, 251 KB

english, 1973

9

Generation of hepatocytes expressing functional cytochromes P450 from a pancreatic progenitor cell line in vitro

MAREK, Carylyn J., CAMERON, Gary A., ELRICK, Lucy J., HAWKSWORTH, Gabrielle M., WRIGHT, Matthew C.

Journal:

Biochemical Journal

Year:

2003

Language:

english

File:

PDF, 201 KB

english, 2003

10

STOMACH CANCER AFTER GASTRIC OPERATIONS FOR BENIGN CONDITIONS

Drasar, B.S, Hill, M.J, Hawksworth, Gabrielle

Journal:

Year:

1971

Language:

english

File:

PDF, 169 KB

english, 1971

11

Changes in rat hepatic UDP-glucuronosyltransferase activity after induction of hyper- or hypothyroidism are substrate dependent

PENNINGTON, JULIE, SCOTT, ANDREW K., REID, IVAN W., HAWKSWORTH, GABRIELLE, M.

Journal:

Biochemical Society Transactions

Year:

1988

Language:

english

File:

PDF, 227 KB

english, 1988

12

Use of toxicokinetics to support chemical evaluation: Informing high dose selection and study interpretation

Stuart Creton, Shakil A. Saghir, Michael J. Bartels, Richard Billington, James S. Bus, Will Davies, Matthew P. Dent, Gabrielle M. Hawksworth, Simon Parry, Kim Z. Travis

Journal:

Regulatory Toxicology and Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.20 MB

english, 2012

13

PXR and CAR are implicated in Oatp1a4 induction in vivo and in vitro

David E. Cowie, Richard J. Weaver, Gabrielle M. Hawksworth

Journal:

Year:

2006

Language:

english

File:

PDF, 71 KB

english, 2006

14

Diquat alters the localisation of E-cadherin, β-catenin, occludin and ZO-1 in LLC-PK1 cells

Laura C. Young, Gabrielle M. Hawksworth, Carol A. Alderson

Journal:

Year:

2008

Language:

english

File:

PDF, 52 KB

english, 2008

15

Further evidence for the presence of cannabinoid CB1 receptors in mouse vas deferens

Roger G. Pertwee, Gozie Joe-Adigwe, Gabrielle M. Hawksworth

Journal:

European Journal of Pharmacology

Year:

1996

Language:

english

File:

PDF, 352 KB

english, 1996

16

Streptozotocin-induced diabetes is associated with increased renal lipoxygenase activity

Stewart, Victoria C., Whiting, Paul H., Bell, J. Angus, Hawksworth, Gabrielle M.

Journal:

Biochemical Society Transactions

Year:

1998

Language:

english

File:

PDF, 141 KB

english, 1998

17

Drug Metabolism

Gabrielle M Hawksworth

Journal:

Medicine (Medicine Publishing Company Ltd)

Year:

2003

Language:

english

File:

PDF, 66 KB

english, 2003

18

Metallothionein overexpression and resistance to toxic stress

John H. Beattie, Hannah L.H. Owen, Shona M. Wallace, John R. Arthur, In-Sook Kwun, Gabrielle M. Hawksworth, Heather M. Wallace

Journal:

Toxicology Letters

Year:

2005

Language:

english

File:

PDF, 166 KB

english, 2005

19

The activity of UDP-glucuronyltransferase, sulphotransferase and glutathione-S-transferase in primary cultures of rat hepatocytes

M.Helen Grant, Gabrielle M. Hawksworth

Journal:

Biochemical Pharmacology

Year:

1986

Language:

english

File:

PDF, 549 KB

english, 1986

20

The immediate early genes, c-fos, c-jun and AP-1, are early markers of platinum analogue toxicity in human proximal tubular cell primary cultures

Richard David Wainford, Richard J. Weaver, Gabrielle M. Hawksworth

Journal:

Toxicology in Vitro

Year:

2009

Language:

english

File:

PDF, 675 KB

english, 2009

21

Maintenance of mixed-function oxidase activities in primary cultures of rat hepatocytes

LINDSAY, CAROL K., ROTONDO, DINO, GRANT, M. HELEN, HAWKSWORTH, GABRIELLE M.

Journal:

Biochemical Society Transactions

Year:

1989

Language:

english

File:

PDF, 249 KB

english, 1989

22

66 Theta-class glutathione S-transferases in human kidney and renal tumours

Veitch, James M, Murray, Graeme I, Juronen, Erkki, Kilty, Cormac, G., Doyle, Sean, Hawksworth, Gabrielle M, Rodilla, Vicente

Journal:

Biochemical Society Transactions

Year:

1997

Language:

english

File:

PDF, 181 KB

english, 1997

23

Transepithelial resistance and transporters in human and porcine renal cell lines

Carol A. Alderson, Gavin Ryan, Gordon McEwan, Michael P. Ryan, Gabrielle M. Hawksworth

Journal:

Year:

2007

Language:

english

File:

PDF, 53 KB

english, 2007

24

67 Conjugation of 1,2-epoxy-3-(p-nitrophenoxy)-propane and 1-menaphthyl sulfate with glutathione in human renal cortex and renal carcinomas

Veitch, James M, Hawksworth, Gabrielle M, Rodilla, Vicente

Journal:

Biochemical Society Transactions

Year:

1997

Language:

english

File:

PDF, 106 KB

english, 1997

25

Role of PXR And FXR in the transcriptional regulation of Oatps

Laura C. Young, David E. Cowie, Richard J. Weaver, Gabrielle M. Hawksworth

Journal:

Year:

2009

Language:

english

File:

PDF, 65 KB

english, 2009

26

Biliary excretion of 5 (and 6)-carboxy-2′,7′-dichlorofluorescein (CDF) by multidrug resistance-associated protein 2 (Mrp2) in rat hepatocyte cultures

Lucy C.J. Ellis, Richard J. Weaver, Gabrielle M. Hawksworth

Journal:

Year:

2007

Language:

english

File:

PDF, 55 KB

english, 2007

27

Differential expression and synthesis of natriuretic peptides determines natriuretic peptide receptor expression in primary cultures of human proximal tubular cells

Mistry, Sanjay K., Hawksworth, Gabrielle M., Struthers, Alan D., McLay, James S.

Journal:

Journal of Hypertension

Year:

2001

Language:

english

File:

PDF, 953 KB

english, 2001

28

Isolation and characterization of rat renal proximal tubular cells

GORDON, ELAINE M., WHITING, PAUL H., SIMPSON, JOHN G., HAWKSWORTH, GABRIELLE M.

Journal:

Biochemical Society Transactions

Year:

1987

Language:

english

File:

PDF, 245 KB

english, 1987

29

68 Fetal calf serum decreases CYP3A induction in rat but not in dog or human hepatocyte cultures

JACKSON, FIONA C, CHENERY, RICHARD J, HAWKSWORTH, GABRIELLE M

Journal:

Biochemical Society Transactions

Year:

1997

Language:

english

File:

PDF, 116 KB

english, 1997

30

Effect of Oxprenolol on the Pharmacokinetics and Pharmacodynamics of Hydralazine

Dr Gabrielle M. Hawksworth,A. M. Dart,C. S. Chiang,K. Parry,J. C. Petrie

Journal:

Year:

1983

Language:

english

File:

PDF, 592 KB

english, 1983

31

Transcriptional Regulation of Abcc1–6 (Multidrug Resistance Associated Protein 1–6) in Rat Hepatocytes

Lucy C.J. Ellis, Richard J. Weaver, Gabrielle M. Hawksworth

Journal:

Year:

2009

Language:

english

File:

PDF, 133 KB

english, 2009

32

Isoenzyme-specific induction of cytochromes P -450 in rat hepatocytes cultured in the presence of dimethylsulphoxide

LINDSAY, CAROL K., BURKE, M. DANNY, WEAVER, RICHARD J., MELVIN, WILLIAM T., HAWKSWORTH, GABRIELLE M.

Journal:

Biochemical Society Transactions

Year:

1990

Language:

english

File:

PDF, 225 KB

english, 1990

33

The Practical Applicability of Hepatocyte Cultures in Routine Testing

Blaauboer, Bas J., Boobis, Alan R., Castell, Jose V., Coecke, Sandra, Groothuis, Geny M.M., Guillouzo, Andre, Hall, Tony J., Hawksworth, Gabrielle M., Lorenzon, Giocondo, Miltenburger, Herbert G., Rog

Journal:

Alternatives to laboratory animals : ATLA

Year:

1994

File:

PDF, 939 KB

1994

34

Nitric oxide production by human proximal tubular cells: A novel immunomodulatory mechanism?

McLay, James S, Chatterjee, Prabal, Nicolson, A Graham, Jardine, Allan G, McKay, Neil G, Ralston, Stuart H, Grabowski, Peter, Haites, Neva E, MacLeod, Allison M, Hawksworth, Gabrielle M

Journal:

Kidney International

Year:

1994

Language:

english

File:

PDF, 606 KB

english, 1994

35

Kinetics of paraquat elimination in the dog

Gabrielle M. Hawksworth, Peter N. Bennett, Donald S. Davies

Journal:

Toxicology and Applied Pharmacology

Year:

1981

Language:

english

File:

PDF, 491 KB

english, 1981

36

Human adult hepatocytes in primary monolayer culture: Maintenance of mixed function oxidase and conjugation pathways of drug metabolism

M.Helen Grant, M.Danny Burke, Gabrielle M. Hawksworth, Susan J. Duthie, Jetmund Engeset, James C. Petrie

Journal:

Biochemical Pharmacology

Year:

1987

Language:

english

File:

PDF, 666 KB

english, 1987

37

Substrate-specific glucuronidation in rat hepatocytes

PRITCHARD, MICHAEL P., HAWKSWORTH, GABRIELLE M.

Journal:

Biochemical Society Transactions

Year:

1990

Language:

english

File:

PDF, 207 KB

english, 1990

38

Cryopreservation of rat hepatocytes with high attachment efficiency and mixed function oxidase activity post thawing

DESAI, AMAR D. J., HAWKSWORTH, GABRIELLE M.

Journal:

Biochemical Society Transactions

Year:

1990

Language:

english

File:

PDF, 127 KB

english, 1990

39

Exposure of cultured human proximal tubular cells to cadmium, mercury, zinc and bismuth: toxicity and metallothionein induction

Vicente Rodilla, Adrian T. Miles, William Jenner, Gabrielle M. Hawksworth

Journal:

Chemico-Biological Interactions

Year:

1998

Language:

english

File:

PDF, 284 KB

english, 1998

40

Role of nuclear receptors in regulating drug transporters and P450s

Gabrielle Hawksworth

Journal:

Toxicology Letters

Year:

2007

Language:

english

File:

PDF, 68 KB

english, 2007

41

Improved risk assessment of chemicals through the application of toxicokinetic information: Opportunities for the replacement, reduction and refinement of animal use

Stuart Creton, Richard Billington, Will Davies, Matthew P. Dent, Gabrielle M. Hawksworth, Simon Parry, Kim Z. Travis

Journal:

Year:

2009

Language:

english

File:

PDF, 270 KB

english, 2009

42

Transporter mediated uptake and efflux of antiretroviral drugs: Potential for drug–drug interactions

Zoe Riches, Gary A. Cameron, Gabrielle M. Hawksworth

Journal:

Year:

2011

Language:

english

File:

PDF, 102 KB

english, 2011

43

Induction of metallothionein in cultured human proximal tubular cells can protect against cisplatin induced nephrotoxicity

Vicente Rodilla, Jonathan P. Little, Naheed Afzal, Adrian T. Miles, Gabrielle M. Hawksworth

Journal:

Toxicology Letters

Year:

1996

Language:

english

File:

PDF, 125 KB

english, 1996

44

Mechanism of action of the antifibrogenic compound gliotoxin in rat liver cells

James G. Orr, Val Leel, Gary A. Cameron, Carylyn J. Marek, Emma L. Haughton, Lucy J. Elrick, Julie E. Trim, Gabrielle M. Hawksworth, Andrew P. Halestrap, Matthew C. Wright

Journal:

Year:

2004

Language:

english

File:

PDF, 1.27 MB

english, 2004

45

Comparative analysis of indices of in vitro toxicity in a renal cell line

Carol A. Low, Gavin Ryan, Gordon McEwan, Tracey Duff, Michael P. Ryan, Gabrielle M. Hawksworth

Journal:

Year:

2006

Language:

english

File:

PDF, 71 KB

english, 2006

46

Structure–Activity Relationship for Two Lipoxygenase Inhibitors and Their Potential for Inducing Nephrotic Syndrome

Timothy J. Morley, Gareth O. Evans, David A. Goodwin, Nicholas G. Read, Simon T. Hodgson, Gabrielle M. Hawksworth

Journal:

Toxicology and Applied Pharmacology

Year:

1997

Language:

english

File:

PDF, 2.86 MB

english, 1997

47

Transcriptional regulation of the rat Ntcp and Bsep by PXR and FXR in vivo

Muhammad Farooq, Richard J. Weaver, Colin J. Henderson, Gabrielle M. Hawksworth

Journal:

Year:

2011

Language:

english

File:

PDF, 74 KB

english, 2011

48

The effect of activators of glucuronyltransferase in the streptozotocin-induced diabetic rat

M.Helen Morrison, M. Gabrielle, Hawksworth

Journal:

Biochemical Pharmacology

Year:

1982

Language:

english

File:

PDF, 335 KB

english, 1982

49

Morphological alterations induced by cadmium, mercury, zinc and bismuth on cultured human proximal tubular cells

Vicente Rodilla, Adrian T. Miles, Deborah Marshall, Gabrielle M. Hawksworth

Journal:

Toxicology Letters

Year:

1996

Language:

english

File:

PDF, 125 KB

english, 1996

50

Induction of CYP3A enzymes in human and rat hepatocyte cultures

WILLIAMS, J. ANDREW, CHENERY, RICHARD J, HAWKSWORTH, GABRIELLE M.

Journal:

Biochemical Society Transactions

Year:

1994

Language:

english

File:

PDF, 124 KB

english, 1994

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